Real World Beta Cell Preservation Throughout
the Stages of Type 1 Diabetes

Developed with clinical leaders from the T1D Exchange Quality Improvement
Collaborative and grounded in current evidence and real-world implementation experience.

Early-stage T1D care is advancing quickly — implementation takes effort and consideration.

Screening and staging approaches are expanding, and disease-modifying therapies are reshaping early-stage T1D conversations. But integrating these changes into routine practice requires coordinated workflows, referral pathways, staff training and operational readiness.

What you’ll find in this white paper:

• Recommended screening framework and who/when to screen
• Staging and monitoring protocols for early-stage T1D
• Practical clinical pathways for operationalizing early detection
• Considerations for operationalizing disease modifying therapy workflows
• Quality improvement strategies, measures, and benchmarking guidance
• Tools and examples (process maps, workflow illustrations, EHR-related supports)

Questions regarding this white paper can be emailed to QI@t1dexchange.org.

How to Cite This Paper:

Demeterco-Berggren, C, Jacobsen, L, Rioles, N, et al. Beta-Cell Preservation Throughout the Stages of Type 1 Diabetes White Paper. T1D Exchange. 2026. Accessed Month Day, Year. URL.