A Clinical and Implementation Framework from the T1DX-QI Beta Cell Preservation Working Group
Developed with clinical leaders from the T1D Exchange Quality Improvement Collaborative and grounded in current evidence and real-world implementation experience.
Early-stage T1D care is advancing quickly — implementation takes effort and consideration.
Screening and staging approaches are expanding, and disease-modifying therapies are reshaping early-stage T1D conversations. But integrating these changes into routine practice requires coordinated workflows, referral pathways, staff training and operational readiness.
What you’ll find in this white paper:
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Recommended screening framework and who/when to screen
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Staging and monitoring protocols for early-stage T1D
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Practical clinical pathways for operationalizing early detection
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Considerations for operationalizing disease modifying therapy workflows
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Quality improvement strategies, measures, and benchmarking guidance
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Tools and examples (process maps, workflow illustrations, EHR-related supports)
Questions regarding this white paper can be emailed to QI@t1dexchange.org.
How to Cite This Paper:
Demeterco-Berggren, C, Jacobsen, L, Rioles, N, et al. Beta-Cell Preservation Throughout the Stages of Type 1 Diabetes White Paper. T1D Exchange. 2026. Accessed Month Day, Year. URL.