Acute and Chronic Adverse Outcomes of Type 1 Diabetes

KEY POINTS

The Diabetes Control and Complications Trial (DCCT) and the follow-up Epidemiology of Diabetes Interventions and Complications (EDIC) study showed that improving glycemic management is associated with lower rates of complications.
Acute complications can occur in youth and adolescents, and chronic complications can occur as early as the adolescent period.
Guidelines exist for screening and management of complications.
New technologies, including continuous glucose monitors and insulin pumps, have the potential to better understand/address glycemic patterns and decrease rates of bothacute and chronic complications.