Type 1 Diabetes Screening and Diagnosis

KEY POINTS

Deciding who and how to screen for T1D has broad clinical and research implications.
Several screening programs exist with goals of early detection of T1D and possible entry into prevention and/or new-onset trials.
In pediatric patients at increased risk of T1D, OGTT is the gold standard for disease staging and assisting in predicting risk of progression, especially when incorporated in a T1D risk score.
Unless overt symptoms of DM are present at diagnosis, testing should be repeated to
confirm the diagnosis.